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- Investigation of the role of MicroRNA- 223, MicroRNA -381 and MicroRNA- 505 in the regulation of transcription factor NFI-A.
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Introduction
It has been shown that the brain‘s tolerance to ischaemic injuries can be temporarily augmented when exposed to a non-injurious pre-conditioning stimulus (Gidday, 2006). The transcription factor NFI-A, a CCAAT-related binding protein that functions both in viral DNA replication and in the regulation of gene expression was found to be a gene that was upregulated during this phenomenon. It has also been shown to play a role in preconditioning-induced neuroprotective functions (Zh...
Approximate word count: 1928
Approximate pages: 8 (250 words per
double-spaced page) |
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